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1

Preparation and structure-activity relationships of simplified analogs of the antifungal agent cilofungin: a total synthesis approach

Zambias, Robert A., Hammond, Milton L., Heck, James V., Bartizal, Ken, Trainor, Charlotte, Abruzzo, George, Schmatz, Dennis M., Nollstadt, Karl M.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.73 MB

english, 1992

2

In Vitro Activity and Microbiological Efficacy of Tedizolid (TR-700) against Gram-Positive Clinical Isolates from a Phase 2 Study of Oral Tedizolid Phosphate (TR-701) in Patients with Complicated Skin and Skin Structure Infections

Prokocimer, P., Bien, P., DeAnda, C., Pillar, C. M., Bartizal, K.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2012

Language:

english

File:

PDF, 465 KB

english, 2012

3

Synthesis and structure-activity relationships of novel 3′-Hty-substituted pneumocandins

Regina M Black, James M Balkovec, Karl M Nollstadt, Sarah Dreikorn, Kenneth F Bartizal, George K Abruzzo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 361 KB

english, 1997

4

Synthesis and Antifungal Activity of Novel Cationic Pneumocandin Bo Derivatives

Bouffard, F. Aileen, Zambias, Robert A., Dropinski, James F., Balkovec, James M., Hammond, Milton L., Abruzzo, George K., Bartizal, Kenneth F., Marrinan, Jean A., Kurtz, Myra B.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 520 KB

english, 1994

5

ChemInform Abstract: Synthesis and Structure—Activity Relationships of Novel 3′-Hty-Substituted Pneumocandins.

R. M. BLACK, J. M. BALKOVEC, K. M. NOLLSTADT, S. DREIKORN, K. F. BARTIZAL, G. K. ABRUZZO

Journal:

Year:

1998

File:

PDF, 33 KB

1998

6

Depressed liver regeneration after partial hepatectomy of germ-free, athymic and lipopolysaccharide-resistant mice

Robert P. Cornell, Barbara L. Liljequist, Kenneth F. Bartizal

Journal:

Year:

1990

Language:

english

File:

PDF, 816 KB

english, 1990

7

Antifungal lipopeptides: Structure-activity relationships of 3-hydroxyglutamine-modified pneumocandin B0 derivatives

Robert A. Zambias, Catherine James, Milton L. Hammond, George K. Abruzzo, Kenneth F. Bartizal, Karl H. Nollstadt, Cameron Douglas, Jean Marrinan, James M. Balkovec

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 326 KB

english, 1995

8

The isolation and structure elucidation of zaragozic acid C, a novel potent squalene synthase inhibitor.

Claude Dufresne, Kenneth E. Wilson, Deborah Zink, Jack Smith, James D. Bergstrom, Marc Kurtz, Deborah Rew, Mary Nallin, Rosalind Jenkins, Ken Bartizal, Charlotte Trainor, Gerald Bills, Maria Meinz, Le

Journal:

Year:

1992

Language:

english

File:

PDF, 431 KB

english, 1992

9

The synthesis of novel 8a-aza-8a-homoerythromycin derivatives via the beckmann rearrangement of (9z)-erythromycin a oxime

Robert R. Wilkening, Ronald W. Ratcliffe, George A. Doss, Kenneth F. Bartizal, Amy C. Graham, Charmaine M. Herbert

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 510 KB

english, 1993

10

Lipopeptide antifungal agents: Amine conjugates of the semi-synthetic pneumocandins L-731,373 and L-733,560

Robert A. Zambias, Catherine James, George K. Abruzzo, Kenneth F. Bartizal, Richard Hajdu, Randy Thompson, Karl H. Nollstadt, Jean Marrinan, James M. Balkovec

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 353 KB

english, 1997

11

Comparative in vitro activity of ertapenem against bacterial pathogens isolated from patients with lower respiratory tract infections

P. S. Hicks, B. Pelak, G. L. Woods, K. F. Bartizal, M. Motyl

Journal:

Clinical Microbiology and Infection

Year:

2002

Language:

english

File:

PDF, 99 KB

english, 2002

12

Impaired binding of estradiol to vaginal mucosal cells in post-menopausal osteoporosis

F. J. Bartizal, Carolyn B. Coulam, T. A. Gaffey, R. J. Ryan, B. L. Riggs

Journal:

Calcified Tissue International

Year:

1976

Language:

english

File:

PDF, 227 KB

english, 1976

13

Global Distribution and Outcomes forCandidaSpecies Causing Invasive Candidiasis: Results from an International Randomized Double-Blind Study of Caspofungin Versus Amphotericin B for the Treatment of Invasive Candidiasis

A. L. Colombo, J. Perfect, M. DiNubile, K. Bartizal, M. Motyl, P. Hicks, R. Lupinacci, C. Sable, N. Kartsonis

Journal:

European Journal of Clinical Microbiology & Infectious Diseases

Year:

2003

Language:

english

File:

PDF, 131 KB

english, 2003

14

Pneumocandin antifungal lipopeptides. The phenolic hydroxyl is required for 1,3-β-glucan synthesis inhibition.

James M. Balkovec, Regina M. Black, George K. Abruzzo, Ken Bartizal, Sarah Dreikorn, Nollstadt Karl

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 306 KB

english, 1993

15

Controlled amylophagia in female mice

L. Keith, F. Bartizal, E. Brown

Journal:

Cellular and Molecular Life Sciences

Year:

1971

Language:

english

File:

PDF, 240 KB

english, 1971

16

Cholesterol metabolism in gnotobiotic gerbils

Kenneth F. Bartizal, Margaret H. Beaver, Bernard S. Wostmann

Journal:

Year:

1982

Language:

english

File:

PDF, 499 KB

english, 1982

17

A critical review of management of 392 colonic and rectal injuries

John F. Bartizal, David R. Boyd, Frank A. Folk, Durand Smith, Theodore C. Lescher, Robert J. Freeark

Journal:

Diseases of the Colon & Rectum

Year:

1974

Language:

english

File:

PDF, 444 KB

english, 1974

18

Effects of α-adrenergic blockers on visual evoked responses in rabbits

H.C. Sabelli, F. Bartizal, W.J. Giardina, S.B. Myles

Journal:

Electroencephalography and Clinical Neurophysiology

Year:

1972

Language:

english

File:

PDF, 317 KB

english, 1972

19

Comparative in vitro activities of ertapenem against aerobic and facultative bacterial pathogens from patients with complicated skin and skin structure infections

Barbara A Pelak, Ken Bartizal, Gail L Woods, Richard M Gesser, Mary Motyl

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

2002

Language:

english

File:

PDF, 111 KB

english, 2002

20

Synthesis, stability, and biological evaluation of water-soluble prodrugs of a new echinocandin lipopeptide. Discovery of a potential clinical agent for the treatment of systemic candidiasis and Pneumocystis carinii pneumonia (PCP)

Balkovec, James M., Black, Regina M., Hammond, Milton L., Heck, James V., Zambias, Robert A., Abruzzo, George, Bartizal, Ken, Kropp, Helmut, Trainor, Charlotte

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 718 KB

english, 1992

21

Antibacterial Activity of Lonchocarpol A

Salvatore, Michael J., King, Aurora B., Graham, Amy C., Onishi, H. Russell, Bartizal, Kenneth F., Abruzzo, George K., Gill, Charles J., Ramjit, Harri G., Pitzenberger, Steven M., Witherup, Keith M.

Journal:

Journal of Natural Products

Year:

1998

Language:

english

File:

PDF, 32 KB

english, 1998

22

Structure-Activity Relationships of C1 and C6 Side Chains of Zaragozic Acid A Derivatives

Ponpipom, Mitree M., Girotra, Narindar N., Bugianesi, Robert L., Roberts, Cathleen D., Berger, Gregory D., Burk, Robert M., Marquis, Robert W., Parsons, William H., Bartizal, Kenneth F.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 3.18 MB

english, 1994

23

Absorption, Distribution, Metabolism, and Excretion of the Novel Antibacterial Prodrug Tedizolid Phosphate

Ong, V., Flanagan, S., Fang, E., Dreskin, H. J., Locke, J. B., Bartizal, K., Prokocimer, P.

Journal:

Drug Metabolism and Disposition

Year:

2014

Language:

english

File:

PDF, 781 KB

english, 2014

24

Results of the Surveillance of Tedizolid Activity and Resistance Program: in vitro susceptibility of Gram-positive pathogens collected in 2011 and 2012 from the United States and Europe

Sahm, Daniel F., Deane, Jennifer, Bien, Paul A., Locke, Jeffrey B., Zuill, Douglas E., Shaw, Karen J., Bartizal, Ken F.

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

2015

Language:

english

File:

PDF, 406 KB

english, 2015

25

Multicenter evaluation of a broth macrodilution antifungal susceptibility test for yeasts.

Fromtling, R A, Galgiani, J N, Pfaller, M A, Espinel-Ingroff, A, Bartizal, K F, Bartlett, M S, Body, B A, Frey, C, Hall, G, Roberts, G D

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1993

Language:

english

File:

PDF, 1.38 MB

english, 1993

26

Rustmicin, a Potent Antifungal Agent, Inhibits Sphingolipid Synthesis at Inositol Phosphoceramide Synthase

Mandala, S. M., Thornton, R. A., Milligan, J., Rosenbach, M., Garcia-Calvo, M., Bull, H. G., Harris, G., Abruzzo, G. K., Flattery, A. M., Gill, C. J., Bartizal, K., Dreikorn, S., Kurtz, M. B.

Journal:

Journal of Biological Chemistry

Year:

1998

Language:

english

File:

PDF, 746 KB

english, 1998

27

Microbial flora of the external os of the premenopausal cervix.

Keith, L, England, D, Bartizal, F, Brown, E, Fields, C

Journal:

Sexually Transmitted Infections

Year:

1972

Language:

english

File:

PDF, 936 KB

english, 1972

28

In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin.

Bartizal, K, Abruzzo, G, Trainor, C, Krupa, D, Nollstadt, K, Schmatz, D, Schwartz, R, Hammond, M, Balkovec, J, Vanmiddlesworth, F

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1992

Language:

english

File:

PDF, 1.68 MB

english, 1992

29

In vitro evaluation of the pneumocandin antifungal agent L-733560, a new water-soluble hybrid of L-705589 and L-731373

Bartizal, K., Scott, T., Abruzzo, G. K., Gill, C. J., Pacholok, C., Lynch, L., Kropp, H.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1995

Language:

english

File:

PDF, 209 KB

english, 1995

30

Efficacy of the Echinocandin Caspofungin against Disseminated Aspergillosis and Candidiasis in Cyclophosphamide-Induced Immunosuppressed Mice

Abruzzo, G. K., Gill, C. J., Flattery, A. M., Kong, L., Leighton, C., Smith, J. G., Pikounis, V. B., Bartizal, K., Rosen, H.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2000

Language:

english

File:

PDF, 149 KB

english, 2000

31

Caspofungin Susceptibility Testing of Isolates from Patients with Esophageal Candidiasis or Invasive Candidiasis: Relationship of MIC to Treatment Outcome

Kartsonis, N., Killar, J., Mixson, L., Hoe, C.-M., Sable, C., Bartizal, K., Motyl, M.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2005

Language:

english

File:

PDF, 195 KB

english, 2005

32

Simian Immunodeficiency Virus–Infected Macaques Treated with Highly Active Antiretroviral Therapy Have Reduced Central Nervous System Viral Replication and Inflammation but Persistence of Viral DNA

Zink, M. Christine, Brice, Angela K., Kelly, Kathleen M., Queen, Suzanne E., Gama, Lucio, Li, Ming, Adams, Robert J., Bartizal, Christopher, Varrone, John, Rabi, S. Alireza, Graham, David R., Tarwater

Journal:

The Journal of Infectious Diseases

Year:

2010

Language:

english

File:

PDF, 1014 KB

english, 2010

33

Evaluation of water-soluble pneumocandin analogs L-733560, L-705589, and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

Abruzzo, G. K., Flattery, A. M., Gill, C. J., Kong, L., Smith, J. G., Krupa, D., Pikounis, V. B., Kropp, H., Bartizal, K.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1995

Language:

english

File:

PDF, 232 KB

english, 1995

34

In Vivo Efficacy of a Novel Oxazolidinone Compound in Two Mouse Models of Infection

Gill, C. J., Abruzzo, G. K., Flattery, A. M., Misura, A. S., Bartizal, K., Hickey, E. J.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2007

Language:

english

File:

PDF, 108 KB

english, 2007

35

Activity of Tedizolid Phosphate (TR-701) in Murine Models of Infection with Penicillin-Resistant and Penicillin-Sensitive Streptococcus pneumoniae

Choi, S., Im, W., Bartizal, K.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2012

Language:

english

File:

PDF, 194 KB

english, 2012

36

Influences of Methodological Variables on Susceptibility Testing of Caspofungin against Candida Species and Aspergillus fumigatus

Bartizal, C., Odds, F. C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2003

Language:

english

File:

PDF, 87 KB

english, 2003

37

An Alternative to Hemorrhoidectomy

Journal:

Archives of Surgery

Year:

1977

Language:

english

File:

PDF, 313 KB

english, 1977

38

In Vitro, In Vivo, and Clinical Studies of Tedizolid To Assess the Potential for Peripheral or Central Monoamine Oxidase Interactions

Flanagan, S., Bartizal, K., Minassian, S. L., Fang, E., Prokocimer, P.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2013

Language:

english

File:

PDF, 462 KB

english, 2013

39

Comparative In-Vitro Activities of Ertapenem against Aerobic Bacterial Pathogens Isolated from Patients with Complicated Intra-abdominal Infections

Pelak, B.A., Woods, G.L., Teppler, H., Friedland, I., Bartizal, K., Motyl, M.

Journal:

Journal of Chemotherapy

Year:

2002

Language:

english

File:

PDF, 112 KB

english, 2002

40

Evaluation of Experimental Therapeutics in a New Mouse Model of Helicobacter felis Utilizing 16S rRNA Polymerase Chain Reaction for Detection

Smith, J. G., Kong, L., Abruzzo, G. K., Gill, C. J., Flattery, A. M., Scott, P. M., Silver, L., Kropp, H., Bartizal, K.

Journal:

Scandinavian Journal of Gastroenterology

Year:

1997

Language:

english

File:

PDF, 794 KB

english, 1997

41

Efficacy of Caspofungin in the Treatment of Esophageal Candidiasis Resistant to Fluconazole

Kartsonis, Nicholas, DiNubile, Mark J., Bartizal, Ken, Hicks, Patricia Scott, Ryan, Desmond, Sable, Carole A.

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2002

File:

PDF, 388 KB

2002

42

DIAGNOSIS OF SPIGELIAN HERNIA BY COMPUTED TOMOGRAPHY

Papierniak, K. J., Wittenstein, B., Bartizal, J. F., Wielgolewski, J. W., Love, L.

Journal:

Journal of Computer Assisted Tomography

Year:

1983

File:

PDF, 108 KB

1983

43

BLUNT TRAUMA INVOLVING THE COLON AND RECTUM

HOWELL, H. SLADE, BARTIZAL, JOHN F., FREEARK, ROBERT J.

Journal:

The Journal of Trauma Injury Infection and Critical Care

Year:

1976

File:

PDF, 571 KB

1976

44

Caspofungin versus amphotericin B treatment of Aspergillus fumigatus in kidneys of chronically immunosuppressed infected mice

Hickey, Emily, Abruzzo, George, Bowman, Joel, Douglas, Cameron, Gill, Charles, Liberator, Paul, Misura, Andrew, Pikounis, Bill, Bartizal, Ken

Journal:

Year:

2005

Language:

english

File:

PDF, 393 KB

english, 2005

45

CD101: a novel long-acting echinocandin

Zhao, Yanan, Perez, Winder B., Jiménez-Ortigosa, Cristina, Hough, Grayson, Locke, Jeffrey B., Ong, Voon, Bartizal, Ken, Perlin, David S.

Journal:

Cellular Microbiology

Year:

2016

Language:

english

File:

PDF, 647 KB

english, 2016

46

Characterization of In Vitro Resistance Development to the Novel Echinocandin CD101 in Candida Species

Locke, Jeffrey B., Almaguer, Amanda L., Zuill, Douglas E., Bartizal, Ken

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 430 KB

english, 2016

47

Combined Abdominoperineal Resection

Bartizal, John, Slosberg, P.A.

Journal:

Surgical Clinics

Year:

1977

Language:

english

File:

PDF, 815 KB

english, 1977

48

Preclinical Evaluation of the Stability, Safety, and Efficacy of CD101, a Novel Echinocandin

Ong, Voon, Hough, Grayson, Schlosser, Michael, Bartizal, Ken, Balkovec, James M., James, Kenneth D., Krishnan, B. Radha

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 1.11 MB

english, 2016

49

L-687, 781, a new member of the papulacandin family of .BETA.-1,3-d-glucan synthesis inhibitors. I. Fermentation, isolation, and biological activity.

VANMIDDLESWORTH, FRANK, OMSTEAD, MARY NALLIN, SCHMATZ, DENNIS, BARTIZAL, KEN, FROMTLING, ROBERT, BILLS, GERALD, NOLLSTADT, KARL, HONEYCUTT, SUSAN, ZWEERINK, MARCIA, GARRITY, GEORGE, WILSON, KEN

Journal:

The Journal of Antibiotics

Year:

1991

Language:

english

File:

PDF, 405 KB

english, 1991

50

In vivo Evaluation of Three Acid-stable Azalide Compounds, L-701,677, L-708,299 and L-708,365 Compared to Erythromycin, Azithromycin and Clarithromycin.

GILL, CHARLES J., ABRUZZO, GEORGE K., FLATTERY, AMY M., SMITH, JEFFREY G., JACKSON, JESSE, KONG, LI, WILKENING, ROBERT, SHANKARAN, KOTHANDARAMAN, KROPP, HELMUT, BARTIZAL, KEN

Journal:

The Journal of Antibiotics

Year:

1995

Language:

english

File:

PDF, 593 KB

english, 1995